Inhibition of Melanin Formation by Chemical Agents
نویسندگان
چکیده
منابع مشابه
suppression of coke formation in thermal cracking by coke inhibitors
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Transglutaminases catalyze the cross-linking and amine incorporation of proteins, and are implicated in various biological phenomena. Previously, we found a high molecular mass transglutaminase-inhibitory substance produced by Streptomyces lavendulae Y-200 that appeared to be a melanin substance. Here, we report that synthetic tyrosine melanin inhibited various types of transglutaminases. Tyros...
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ELANIN PIGMENTATION has aroused the curiosity and attention of man since the beginning of recorded history. This interest stems in part from the social, protective and cosmetic significance of pigmentation. In addition, much interest has arisen concerning the possible role of melanin formation in the development of the melanoma which has been described as having the most sinister reputation of ...
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Melanin contained in pigment cells in a variety of tissues co-purifies with nucleic acids in standard RNA (or DNA) extraction procedures. The presence of melanin in RNA (or DNA) templates can inhibit reverse transcription polymerase chain reactions (RT-PCR) and/or PCR (5). In the past, to circumvent this problem, melanin has been separated from DNA by either columnchromatography (5) or acid-pre...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1952
ISSN: 0022-202X
DOI: 10.1038/jid.1952.16